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Senetek PLC and Age Advantage Laboratories, Inc. Announce Signing of Kinetin License

NAPA, California, October 16, 2003 -- Senetek PLC (NASDAQ: SNTK - News), www.senetekplc.com , and Age Advantage Laboratories, Inc., www.ageadvantagelabs.com, today announced the signing of a license agreement for Age Advantage to formulate its unique "Age Eraser" creme with Senetek's patented Kinetin anti-aging compound and market it in the United States to spas, beauty salons, department stores, high-end perfumeries and natural and health product retailers.

Frank J. Massino, Chairman and Chief Executive Officer of Senetek, said, "We are very pleased that Age Advantage Laboratories has joined our licensee network. Its strength with high-end day and resort spas and beauty salons will put Kinetin in an ideal esthetician-assisted environment where its unique properties can be optimally presented, and we look forward to pursuing other potential combinations of Kinetin with Age Advantage's superb skin treatment formulations. We are also pleased that this license takes us another step closer to achieving Senetek's goal of making Kinetin-based skin care available to consumers across the full spectrum of retail channels of distribution."

Andrew P. Strickman, Chief Executive Officer of Age Advantage Laboratories, said, "We are excited that Senetek has licensed Kinetin for use in Age Advantage Laboratories' 'Age Eraser' skin creme. 'Age Eraser' is a vital part of our skin repair regimen and we believe that the combination of our ingredients with Kinetin clearly makes this the most advanced anti-aging product on the market. With this new alliance, we also hope to develop other products which combine Kinetin with our state of the art formulations. Our goal is to fight the aging process, and Kinetin, a plant-derived compound, moves us toward achieving that goal by helping to prevent the signs and symptoms of premature skin aging and slowing the aging process of the cells, naturally and without irritation."

Age Eraser from Age Advantage Laboratories has received significant praise from beauty experts such as Kat James. Author of "The Truth About Beauty," James writes, "This is one of the most impressive Kinetin products I've found."

Senetek's patented ingredient, Kinetin, is a naturally occurring cytokinin that has proven to be effective in treating the appearance of aging skin with virtually none of the side effects associated with acid-based active ingredients. Senetek's ten other licensees include ICN Pharmaceuticals, Inc., Revlon, Inc. and The Body Shop, which have successfully introduced Kinetin in their respective channels of distribution.

Headquartered in Atlanta, Georgia, Age Advantage Laboratories offers natural anti-aging and skin repair products that deliver solutions for outer beauty and inner health, principally through natural food stores, pharmacies, specialty stores, spas and salons nationwide.