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Monday February 9, 7:00 am ET
TULSA, Okla.--(BUSINESS WIRE)--Feb. 9, 2004--Centrex, Inc. (OTCBB:CNEX - News) today announced that Micronics, Inc., has advanced the development of an assay that contains Centrex's single molecule nucleic acid detection ("SMD") technology for application in a laboratory-on-a-card ("lab card") format. Micronics reported to Centrex that it has achieved this important initial milestone which permits lysis and binding reactions in the lab card format.
SMD technology, in combination with an easy-to-operate lab card device and integrated reader, is expected to be responsive to the need for rapid, user friendly and cost effective solutions for point-of-use analyses of a variety of bacterial and viral organisms.
Centrex's SMD technology was exclusively licensed from Los Alamos National Laboratories, and offers important advantages over existing DNA and RNA detection methods as well as culture-based test methods. SMD technology eliminates the need for amplification of the target DNA by recognizing the unique DNA or RNA fingerprint of the target organism. This reduces the possibility of false positive and negative test results - common concerns frequently identified with other test procedures.
As a next step in the development process, Micronics is expected to integrate the lysing/binding reactions together with SMD using a biological stimulant, the spores of the bacteria Bacillus globigii. Bacillus globigii prepared in this manner may be used safely to simulate Bacillus anthracis (anthrax) spores in the DNA extraction and binding experiments.
Centrex is focusing commercial efforts in the development of a product that uses SMD as part of a simultaneous, multi-channel detection system that is compact, fully automated and capable of monitoring the presence of biological agents in air, food and water. Potential additional applications for the SMD technology include bioterrorism and Homeland Security, food and water processing, blood supply screening, and general DNA/RNA testing.
Redmond, Washington-based Micronics provides custom lab card design, development and prototypes systems. The proposed lab card for the Centrex system is expected to include fully automated on-card sample preparation, mixing, separation, and analysis. Reagent and waste storage also are designed to be on card for ease of use and disposal. Micronics is believed to offer the most sophisticated and rapid lab card prototyping facility in the world today. For additional information please visit
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